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Open-label placebos Mind over medicine

Placebos can help even when you know.

Five evidence-based protocols that harness your brain's own pharmacy to improve your condition.

Designed using research from the world's leading institutions

Harvard Medical School Columbia University Dana-Farber Cancer Institute MD Anderson Cancer Center University of Maryland School of Medicine Universität Zürich Universität Marburg Universität Leipzig

The founding study

2010

A groundbreaking Harvard study showed that an honest placebo could actually help patients.[1]

2× Relief reported almost twice as often vs. control
1,250+ Citations across other peer-reviewed publications
OLP Kicked off the field known as Open Label Placebos

This incredible trial showed that IBS patients who received honest placebos reported clinically meaningful relief almost twice as frequently vs control. This kicked off an entirely new field of research into honest placebos, called Open Label Placebos (OLPs) and has been cited more than 1250 times in other publications.

Kaptchuk et al. (2010) — Placebos without Deception: A Randomized Controlled Trial in IBS. Published in PLoS ONE.
Kaptchuk T.J. et al. · PLoS ONE, 2010

[1] Kaptchuk T.J. et al. (2010). “Placebos without Deception: A Randomized Controlled Trial in Irritable Bowel Syndrome.” PLoS ONE 5(12):e15591. View study →


Gold-standard science

Gold-standard science has confirmed the positive effect of honest placebos across conditions.

A hand writing on a Copables 'Mapping Your Triggers' protocol card with a copables-branded pen.

Analog × Digital

But not everyone can participate in a research study at Harvard.

Copables creates science-backed 14 day protocols that use placebos and cognitive restructuring to replicate participation in the research studies from home.

How over what

The science shows that how you take something can matter just as much as what you are taking.


Inside-out

Your brain has its own pharmacy. It just needs to be unlocked.

Studies have shown that non-deceptive placebos can cause your brain to produce the very same symptom-relieving chemicals present in real pharmacology.

See the Science
A hand pouring Copables OLP gummies into an open palm, next to a five-star review reading 'I woke up feeling actually rested.'
Five Copables OLP protocol bottles lined up: OLP-1 Low Mood, OLP-2 IBS, OLP-3 Anxiety, OLP-4 PMS, OLP-5 Fatigue.

A new field

Placebos are one of the most underutilized tools in modern medicine.

Open Label Placebos are an emerging field of research whose benefits lie locked away in research labs. Until now.

View 272 OLP publications in PubMed

Copables is an anagram of the word “placebos.”

A bottle of Copables OLP gummies tipped on its side with red gummies spilling out.

Why try it

A sensible place to start.

Open-label placebos don't work for everyone — but they're a low-stakes intervention that might. If you're serious about wanting to feel better, we'd recommend trying this lightweight approach before moving on to more drastic measures.

Check to see if you're a good candidate for OLP.
View all protocols →